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张宪省 博士、教授 山东农业大学副校长,中国植物学会植物细胞生物学与生物技术专业委员会副主任,山东省植物学会副理事长,中国作物学会作物生物技术分会理事,中国作物学会分子育种分会理事。 《Molecular Plant》、《Journal of Integrative Plant Biology》和《植物学通报》编委。
1982年毕业于山东农业大学农学系, 主要从事植物分子生物学和作物生物技术的研究工作,近5年先后主持国家“973”项目、国家转基因植物与产业化专项重点项目,国家高科技计划“863”项目和国家自然科学基金等课题的研究工作。今年被聘为国家重大科学研究计划“植物授粉细胞识别的分子机理研究信号通路”项目首席科学家。先后应邀在国际和国内学术会议做大会报告。培养博士和硕士研究生40余人。获山东省自然科学奖和科技进步奖四项,申请基因发明专利五项,发表学术论文60余篇。1998年享受国务院特殊津贴,1999年入选国家百千万人才工程第一,二层次。
主要研究方向: 方向一,植物发育的分子基础。研究植物发育的分子机理不仅具有重大的科学意义,而且亦为改良植物,满足人类的需求奠定重要的理论基础。本研究方向主要研究植物开花时间、花器官发育、授粉、种子发育等重要发育问题,特别重视研究激素调节植物生殖器官发育的分子机制。研究目的旨在解析上述发育过程的基因调控网络,阐明植物发育的细胞分子基础。 方向二,植物基因工程。本研究方向主要利用植物分子生物学研究的成果和基因工程技术,改良作物的淀粉品质和营养品质,提高作物产量,产品直接服务于农业和工业生产。 目前实验室在研的科研项目: 1. 重大科学研究计划项目(973计划):植物授粉细胞识别的分子机理研究信号通路(编号2007CB947600),2007~2011年,经费2500 万元,项目首席科学家。 2. 重大科学研究计划项目(973计划):植物干细胞维持和分化的分子机理研究(编号2007CB948200),2007~2011年,经费150 万元。 3. 863计划项目:小麦开花时间重要功能基因的鉴定及作用机理的研究(编号),2006~2008年,经费70万元。 4. 973计划项目:水稻重要农艺性状的功能基因组和分子基础研究(编号2005CB120803),2005~2009年,经费40万元。 5. 重大基础研究前期研究专项:小麦和玉米淀粉形成的分子机制及淀粉品质的遗传改良(编号2004CCA06900),2005~2007年,经费50万元。 6. 国家自然科学基金课题:植物离体生殖器官发生过程中细胞脱分化与再分化的分子基础研究(编号30770217),2008~2010年,经费40 万元。 7. 国家自然科学基金课题:保卫细胞微丝骨架调节液泡动态及其调节机理的研究(编号30770193),2008~2010年,经费30 万元。 发表的主要论文: 1. Guo J, Song J, Wang F, Zhang XS. Genome-wide identification and expression analysis of rice cell cycle genes. Plant Molecular Biology (accepted) 2. Qiao WH, Zhao XY, Li W, Zhang XS. Characterization of a root-specific vacuolar Na+/H+ antiporter gene in Agropyron elongatum and its expression involved in the salt tolerance of plants. Plant Cell Reports (accepted) 3. Dong YX, Zhao XY, Zhang XS. Selection of partial waxy wheat lines with ideal agronomic traits by a PCR-based DNA marker. Acta Genetica Sinica (revised) 4. Guo SJ, Zhou HY, Zhang XS, Li XG, Meng QW. (2007) Overexpression of CaHSP26 in transgenic tobacco alleviates photoinhibition of PSII and PSI during chilling stress under low irradiance. Journal of Plant Phsiology 164:126-136 5. Chu ZQ, Chen H, Zhang YY, Zhang ZH, Zheng NY, Yin BJ, Yan HY, Zhu L, Zhao XY, Yuan M, Zhang XS, and Xie Q. (2007) Knockout of the AtCESA2 gene affects microtubule orientation and causes abnormal cell expansion in Arabiodpsis thaliana. Plant Physiology143:213-224 6. Ma XJ, Tao Y, Zhao XY, Zhang XS. (2007) Wheat TaAS2, a member of LOB-Domain family, affects the adaxial-abaxial polarity of leaves in transgenic Arabidopsis. Plant Science 172: 181-188 7. Wang F, Huo SN, Guo J, Zhang XS. (2006) Wheat D-Type cyclin Triae;CYCD2;1 regulate development of transgenic Arabidopsis plants. Planta 224:1129-1140 8. Guan CM, Zhu SS, Li XG, Zhang XS. (2006) Inflorescence induction by hormones from Arabidopsis callus in vitro. Plant Cell Reports 25:1133-1137 9. Zhao W, Su HY, Song J, Zhao XY, Zhang XS. (2006) Ectopic expression of TaYAB1, a member of YABBY gene family in wheat, causes the partial abaxialization of the adaxial epidermises of leaves and arrests the development of shoot apical meristem in Arabidopsis, Plant Science 170:364-371 10. Guo SJ, Li JR, Qiao WH, Zhang XS. (2006) Analysis of amylose accumulation during seed development of maize. Acta Genetica Sinica 32:846-854 11. Zhao XY, Liu MS, Li JR, Guan CM, Zhang XS. (2005) The wheat TaGI1, involved in photoperoidic flowering, encodes an Arabidopsis GI ortholog. Plant Molecular Biology 58:53-64 12. Zhao XY, Cheng ZJ, Zhang XS. (2005) Overexpression of TaMADS1, a SEPALLATA-like gene in wheat, causes early flowering and the abnormal development of floral organs in Arabidopsis. Planta 223:698-707 13. Su HY, Li QZ, Li XG, Zhang XS. (2005) Characterization and expression analysis of a MADS box gene, HoMADS2, in Hyacinthus orientalis L. Acta Genetica Sinica 32: 1191-1198 14. Liu MS, Wang F, Dong YX, Zhang XS. (2005) Expression analysis of dihydroflavonol 4-reductase genes involved in anthocyanin biosynthesis in purple grains of Triticum aestivum. Journal of Intergrative Plant Biology 47 (9): 1107-1114 15. Li JR, Zhao W, Li QZ, Ye XG, An BY, Li X, Zhang XS. (2005) RNA Silencing of waxy gene results in low levels of amylose in the seeds of transgenic wheat (Triticum aestivum L.). Acta Genetica Sinica 32: 846-854 16. Xu HY, Li XG, Li QZ, Bai SN, Lu WL, Zhang XS. (2004) Characterization of HoMADS1 and its induction by plant hormones during in vitro development in Hyacinthus orientalis L. Plant Molecular Biology 55:209-220 17. Lan LF, Chen W, Lai Y, Suo JF, Kong ZS, Can Li, Lu Y, Zhang YJ, Zhao XY, Zhang XS, Zhang YS, Han B, Cheng J, Xue YB. (2004) Mornitoring of gene expression profiles and isolation of candidate genes involved in pollination and fertilization in rice (Oryza sativa L.) using 10K cDNA microarray. Plant Molecular Biology 54:471-483 18. An YR, Li XG, Su HY, Zhang XS. (2004) Pistil induction by hormones from callus of Oryza sativa in vitro. Plant Cell Reports 23:448-452 19. Li JR, Wang F, Zhao XY, Dong YX, Zhang LY, An BY, Zhang XS. (2004) Analysis of Seed Expressed Sequence Tags in Triticum aestivum. Acta Botanica Sinica 46 (3): 363-370 20. Zhang XS, Wang X, Li QZ, Huo SN, Li XG, Ye BX. (2003) A seed-specific gene RS6, encodes a putative cupin domain protein, is essential for seed development in Oryza sativa L. The Annual Meeting of the American Society of Plant Biologists, Plant Biology, Abstract p491 21. Li QZ, Li XG, Bai SN, Lu WL, Zhang XS. (2002) Isolation of HAG1 and its regulation by plant hormones during in vitro floral organogenesis in Hyacinthus orientalis L. Planta 215:533-540 22. Li QZ, Li XG, Bai SN, Lu WL, Zhang XS. (2001) Isolation and expression of HAP2 in Hyacinthus orientalis L. Development & Reproductive Biology10: 69-75 23. Zhang XS, Li QZ, Li XG, Bai SN, Lu WL. (2001) Molecular cloning and expression analysis of HAG1 in the floral organs of Hyacinthus orientalis L. Science in China C, 2000, 43: 395-401 24. Zhang XS, Li QZ, Li XG, Bai SN, Lu WL. (2000) Regulation of homeotic gene expression in the regenerated flowers of Hyacinthus. Plant Biology, The Annual Meeting of the American Society of Plant Physiologists 80: p39 25. Li QZ, Li XG, Sun JQ, Zhang XS. (2000) Isolation and expression of an AGAMOUS homolog in the flower of Cucumber (Cucumis sativas L.). Development & Reproductive Biology 9: 69-76 26. Zhang XS, Zheng CC, O'Neill SD. (1999) Expression of ethylene biosynthetic genes regulated by pollination-associated factors in Doritaenopsis flowers. Acta Botanica Sinica 41 (5): 468-471 27. Zheng CC, Zhang XS. (1999) Cloning and characterization of a circadian rhythm-regulated psaH cDNA in Pharbitis nil. Acta Botanica Sinica 41 (8): 820-824 28. Zhang XS, Li QZ, Zheng CC. (1999) Hormonal regulation of postpollination development of Doritaenopsis flowers by auxin and ethylene. Acta Phytophysiologica Sinica 25 (2): 178-186 29. Wang L, Zhang XS, Zhong HW, Li QZ. (1999) Expression and sequence analysis of a cDNA relative to Orchid ovule development. Acta Botanica Sinica 41(3): 276-279 30. Nadeau JA, Zhang XS, Li J, O'Neill SD. (1996) Ovule development: Identification of stage-specific and tissue-specific cDNAs. Plant Cell 8:213-239 31. O'Neill SD, Zhang XS, Zheng CC. (1994) Dark and circadian regulation of mRNA accumulation associated with photoperiodic flower induction. Plant Physiology104:569-580 32. Zhang XS, Nadeau JA, Li J, O'Neill SD. (1994) Isolation of cDNA clones specific to developing and mature ovules of orchid flowers. Plant Physiology 124: Supplement 33. Zhang XS, O'Neill SD. (1993) Ovary and gametophyte development are coordinately regulated by auxin and ethylene following pollination. Plant Cell 5:403-418 34. Nadeau JA, Zhang XS, Nair H, O'Neill SD. (1993) Temporal and spatial regulation of 1-aminocyclopropane-1-carboxylate oxidase in the pollination-induced senescence of orchid flowers. Plant Physiology 103:31-39 35. O'Neill SD, Nadeau JA, Zhang XS, Bui AQ, Hallevy AH. (1993) Interorgan regulation of ethylene biosynthetic genes by pollination. Plant Cell 5:419-432 奖励: 高等植物花发育的分子生物学研究, 1997, 山东省科技进步二等奖。 小麦品质性状基因的分离与淀粉品质性状的遗传改良, 2005, 山东省自然科学二等奖。 专利: 1、小麦周期蛋白基因及其分离方法与应用, 2002, 专利号021355444。 2、偃麦草钠离子反向转运蛋白基因及其克隆与应用,2002,专利号021355452。 3、紫色小麦二氢黄醇酮还原酶基因及其克隆与应用, 2005, 专利号2004100359148。 4、小麦TaGI1基因及其克隆与应用, 2005, 专利号2004100359167。
5、紫花苜蓿反向转运蛋白基因及其克隆与应用,2005,专利号2004100359152。 |
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